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Concurrently, DON impaired transmembrane transport and lipid homeostasis by suppressing genes such as ATP-binding cassette subfamily A member 4 (ABCA4) 73 , whereas GA induced transporters for detoxification and lipid efflux (e.g., ABCB11 74 and ABCA1 75 )

Clinical Effectiveness

Market Definition Glucagon-like peptide 1 (GLP-1) agonists, alternatively termed GLP-1 receptor agonists, are drugs designed to mimic the incretin hormone glucagon-like peptide-1 (GLP-1)

These observations receive the support of our current and previous functional data showing that both GIP and GLP-1 were unable to activate GCGR (Supplementary Table 6) 5,6