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Protective effect of ginseng berry saponin conversion products on skin photodamage caused by UVB in vitro and in vivo

Exposure to toxins: Pesticides, heavy metals, pollution, household chemicals, and cigarette smoke overwhelm the detox system, which can cause glutathione deficiency

Vitamin D deficiency is common, in part because people who are sick tend to stay at home and not get enough sunshine

When administered intravenously or through injection, the Vitamin B12 is not subject to gut absorption and the entire dosage administered is available to the body for use

However, in resistant patients, oxidative stress causes a conformational change in Keap1, leading to the release of NRF2, which translocates to the nucleus and binds to antioxidant response element (ARE), activating the expression of downstream antioxidant genes, including GPX4, NQO1, HO-1 and SOD1 [33], and promoting the synthesis of GSH, as illustrated in Fig