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Mutations in these regions can disturb GTP binding and lead to decreased sensitivity of GDH to allosteric regulation by GTP, resulting in weakened inhibitory effect and enhanced GDH activity [12]

Graf and Kastins review left the mechanism unresolved, [2] and it has not been resolved since

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Company Profile Anhui GSH Bio Technology Co., Ltd., established in 2010, It is an innovative high-tech enterprise with the core of enzyme catalysis technology in the field of synthetic biology and the interdisciplinary application of multidisciplinary technology

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