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Clinical trial participants who maintained protein intake above 90g daily during Retatrutide treatment showed significantly better lean mass retention than those who let protein intake decline with overall appetite

Abbass NJ, Nahlawi R, Shaia JK, Allan KC, Kaelber DC, Talcott KE, et al

Non-Scale Victories The scale measures total body mass including muscle, water, bone, and everything else

Tirzepatide May Be Right for You If You have a BMI of 30 or higher, or 27 or higher with a weight-related health condition You want an FDA-approved medication with well-established clinical evidence You have type 2 diabetes and want to address both blood sugar and weight You prefer a treatment with extensive real-world safety data You have responded well to GLP-1 medications in the past and want enhanced results Retatrutide May Be Worth Discussing If You have significant weight to lose and want a more aggressive metabolic approach Previous dual-agonist or single-agonist therapies have plateaued You are interested in emerging therapies and are comfortable with newer clinical data You have concerns about fatty liver disease, given retatrutides potential hepatic benefits You want a treatment that addresses both appetite suppression and energy expenditure Important Medical Considerations Neither medication is appropriate for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Subclinical hypothyroidism and elevated aminotransferases: NHANES 2007-2012