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At least one serious adverse event occurred among 10.9% of the 36 mg orforglipron group, 10.3% of the 12 mg orforglipron group, 7.3% of those receiving 6 mg orforglipron and 8.8% of the placebo group

One KFF analysis estimates that roughly 36 million non-elderly Americans with employer coverage alone meet BMI criteria for a GLP-1, while only a small fraction are taking one today, which points to large latent demand constrained by cost