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The SURMOUNT-5 head-to-head results demonstrated tirzepatide led to greater weight reduction compared to semaglutide, providing further evidence to support tirzepatide as an effective option for obesity management. Weight change In SURMOUNT-5, adults aged 18 years and older with overweight or obesity were randomly assigned to the maximum tolerated dose of tirzepatide or semaglutide for 72 weeks (mean age, 44.7 years

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