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Impaired activity of methionine synthase results in elevated blood concentrations of homocysteine, while impaired activity of L-methylmalonyl-CoA mutase results in increased concentrations of a metabolite of methylmalonyl-CoA called methylmalonic acid (MMA) in blood and urine

In the light of the above, circadian misalignment can result from: (1) damage to cerebral structures like the retina, the retino-hypothalamic tract or the SCN

GIP (glucose-dependent insulinotropic polypeptide) further enhances insulin sensitivity and may directly influence fat metabolism in adipose tissue

This is plausible biology, not demonstrated hair regrowth

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