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No large randomized controlled trial directly compares monotherapy against the combination, and what exists is limited observational data and small case series suggesting an additive effect

For brain tumor treatment in particular, the systems are required to have a capability of both BBB crossing and tumor targeting

Comparatively, Wegovy is prescribed for weight loss and comes at a higher dose

While not everyone will experience these adverse effects, its important to be aware of them so you can recognize and manage any issues that may arise