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Alterations in NAD metabolism are critically linked to neurodegenerative disorders, as the accumulation of nicotinamide mononucleotide exerts pro-degenerative effects on axons, whereas enhancing its metabolism may rescue axons from degeneration (13, 53)
The circadian gene PER1 is a protein that helps regulate the circadian rhythm and is usually overexpressed in cancer patients
Survival was recorded until natural death or humane euthanasia
It is possible the ongoing inflammatory injury processes related to mTBI exacerbated oxidative stress in this region
It is possible therefore that a poor gut biome, or indeed even the source of ALCAR/LC may be important in describing outcomes
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