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This includes matrix metalloproteinases (MMPs), which are associated with the breakdown and restructuring of proteins such as collagen and elastin
To bridge this gap, the field must pivot from proof-of-concept studies to rigorous translational validation
Very recent study found significant improvement of behavioral deficits including cognitive decline, depressive-like behaviors, in APP (NLG-F/NLG-FG-) mice due to oral GSH administration
Elimova E, Kim SM, Wang X, Shimodaira Y, Sohn BH, Skinner HD, Lee JH, Weston BR, Bhutani MS, Minsky B, Rice DC, Hwang JE, Swisher SG , Hofstetter W, Blum MA, Maru D, Ajani JA, Lee JS
Persistence should not be judged by staying on a single drug indefinitely, but by maintaining engagement in care and working with clinicians to find sustainable, effective treatment strategies over time, she said in a news release
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