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Among them, 12/15-LOX activity is significantly upregulated in AD brains, and its inhibition rescues memory and learning deficits in mouse models (303)
The goal here is to correct a specific medical problem
All authors contributed to the study conception and design
183 The recruitment of these proteins leads to the formation of the death-inducing signaling complex, which induces the internalization of the receptor, and apoptotic reactions ensure via either caspase- or mitochondrial-mediated cascades
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