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Intriguingly, physiological activation of the androgen receptor has been demonstrated to promote ROS production [23]
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They found a linear relationship between serum UA concentrations and those in cerebrospinal fluid ( r = 0.669, P = 0.001)
CARS2 mutant lacking the persulfide synthesis activity did not rescue the decreased mitochondrial membrane potential of CASR2-deficient cells, whereas CARS2 mutant lacking cysteinyl t-RNA synthesis activity did
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