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Month 3 and Beyond: This is the phase of systemic support

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As your body works harder to regulate temperature, it can experience electrolyte imbalances , low-grade inflammation , oxidative stress , and cellular DNA damage

Of note, GLS1 inhibition causes an elevation of the ROS level and induces GPT2 expression via ATF4, which again implies the importance of ATF4-mediated metabolic adaption during glutamine starvation

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