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Discuss timing with a healthcare provider if you are on oral medications, particularly those for thyroid conditions, blood pressure, or diabetes

Simultaneously, its GLP-1 receptor agonist activity promotes glucose-dependent insulin release, slows gastric emptying, and reduces appetite through central nervous system pathways

Whilst blood in stool is not a recognised adverse reaction in the MHRA-approved Summary of Product Characteristics, patients may experience gastrointestinal side effectssuch as constipationthat can indirectly contribute to rectal bleeding

*Products under the patent are only for R&D use.

doi:10.1056/NEJMoa2403347 Nissen SE, Nicholls SJ, Sipahi I, et al