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During the remaining duration of medication beyond the first month, there is little noticeable difference in the occurrence probability of adverse events between the two administration routes

Timeline Estimates: Based on typical pharmaceutical development, if Eli Lilly started Phase 1 trials for oral tirzepatide today, FDA approval would likely be 5-7 years away at minimum

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"The Reddit community, I think, by being active and voicing their opinions on these things will hopefully, you know sort of encourage the research to more scientifically validate it," said Cohen

All this suggests that acetylcholine could be a transmitter in a neural stimulatory pathway for GLP-1 secretion