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These medications mimic the effects of GLP-1 in the body
We previously reported that reduced levels of activated hepatocyte growth factor and the c-Met receptor tyrosine kinaseboth of which are vital for maintaining cellular redox balancecombined with increased expression of GJ proteins in hepsin-deficient mice
On its own GIP has complex metabolic effects, but when co-activated alongside GLP-1 it appears to amplify weight-loss and glycemic benefits and may improve gastrointestinal tolerability relative to GLP-1 activity alone
Cycling, swimming, or rowing are ideal choices because they are low-impact and add cardiovascular stimulus without excessive joint stress
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