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Accelerating approval of these next-gen formulations by ten to eleven months doesnt change the patent timeline, but it compresses the product cycle: a higher-dose Wegovy and an oral Foundayo reach physicians and patients sooner, generate revenue sooner, establish market position sooner, and create clinical inertia patient stabilization on a specific formulation that makes future price negotiation more difficult for any payer, including CMS

( Epub 20210830 )

However, the involvement of METTL3 or mA modification in cellular reprogramming is complex and context dependent