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The gap between "active in cells and animals" and "safe and effective in humans at a defined dose" is exactly where many promising molecules fail
Clinical studies have shown that some individuals experience small increases in fasting blood glucose or HbA1c during treatment, although these changes are generally modest
Cancers (Basel) 11 , 678 (2019)
Its the tortoise in this race
Based on the results, the researchers suggested that patients prescribed GLP-1s continue the medication prior to a procedure but also follow the standard fasting period and go on a liquid diet the day before, until more research is available
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